BDBM50322527 (2S,3S)-2-(m-Tolyl)-3,5,5-trimethylmorpholin-2-ol::CHEMBL1173277

SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(C)c1

InChI Key InChIKey=RLZACOPBIXSOEX-SMDDNHRTSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322527   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322527((2S,3S)-2-(m-Tolyl)-3,5,5-trimethylmorpholin-2-ol ...)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at alpha4beta2 nicotinic receptor in human SH-EP1 cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed